Posts Tagged ‘Series’
Last Updated on Monday, 5 September 2011 09:25 Written by Administrator Monday, 5 September 2011 09:25
Teratocarcinomas and Embryonic Stem Cells: A Practical Approach (Practical Approach Series)
List Price: $ 62.00
Price:
Tags: Approach, cells, Embryonic, Practical, Series, Stem, Teratocarcinomas | Posted under Stem Cell Books | Comments Off
Last Updated on Wednesday, 31 August 2011 09:26 Written by Administrator Wednesday, 31 August 2011 09:26
Embryonic Stem Cells: A Practical Approach (The Practical Approach Series)
The groundbreaking isolation of embryonic stem cells (or ‘ES cells’) of the mouse in the early 1980s triggered a sustained expansion of global research into their exploitation. This led to the routine genetic engineering of the mouse and revolutionised our understanding of biological processes in the context of the whole animal. ES cell biology remains a crucial and growing area of research with far-reaching implications for developmental and comparative biology as well as for human health.
This book serves as a primer to ES cells, their derivation and experimental manipulation. It contains a broad compendium of methods of direct relevance to both graduate students and specialist researchers. An introductory chapter by the principle originator of ES cell research outlines the fundamentals and charts the development of the field. This is followed by comprehensive coverage of state-of-the art techniques for ES cell manipulation, with the mouse as the experimental paradigm, and by recent innovations with ES cells from human and non-human primates. ES cell-based therapies for otherwise intractable diseases are now being developed with the present challenge to control ES cell growth and differentiation for applications such as cell transplantation – a recurrent theme in this book. As a volume in the Practical Approach Series, the emphasis is on current methods from recognized experts.
List Price: $ 199.00
Price: $ 150.12
Dynamics of Cancer: Incidence, Inheritance, and Evolution (Princeton Series in Evolutionary Biology)
Last Updated on Wednesday, 10 August 2011 09:25 Written by Administrator Wednesday, 10 August 2011 09:25
Dynamics of Cancer: Incidence, Inheritance, and Evolution (Princeton Series in Evolutionary Biology)
The onset of cancer presents one of the most fundamental problems in modern biology. In Dynamics of Cancer, Steven Frank produces the first comprehensive analysis of how particular genetic and environmental causes influence the age of onset.
The book provides a unique conceptual and historical framework for understanding the causes of cancer and other diseases that increase with age. Using a novel quantitative framework of reliability and multistage breakdown, Frank unifies molecular, demographic, and evolutionary levels of analysis. He interprets a wide variety of observations on the age of cancer onset, the genetic and environmental causes of disease, and the organization of tissues with regard to stem cell biology and somatic mutation. Frank uses new quantitative methods to tackle some of the classic problems in cancer biology and aging: how the rate of increase in the incidence of lung cancer declines after individuals quit smoking, the distinction between the dosage of a chemical carcinogen and the time of exposure, and the role of inherited genetic variation in familial patterns of cancer.
This is the only book that presents a full analysis of the age of cancer onset. It is a superb teaching tool and a rich source of ideas for new and experienced researchers. For cancer biologists, population geneticists, evolutionary biologists, and demographers interested in aging, this book provides new insight into disease progression, the inheritance of predisposition to disease, and the evolutionary processes that have shaped organismal design.
List Price: $ 49.95
Price: $ 29.97
Tags: Biology, Cancer, Dynamics, Evolution, Evolutionary, Incidence, Inheritance, Princeton, Series | Posted under Stem Cell Books | Comments Off
Last Updated on Saturday, 9 July 2011 09:25 Written by Administrator Saturday, 9 July 2011 09:25
Commercializing the Stem Cell Sciences (Biohealthcare Publishing Series on Pharma, Biotech and Bioscience: Science Technology)
This book offers a comparative analysis of the commercial models adopted in the global stem cell industries, focusing on case-studies of publicly available information about different companies around the world working on adapting stem cell technologies to market. The case-studies are used to highlight the different possible pipelines for developing stem cell technologies and the issues faced by companies in the competitive global market. Promising new developments in biomedical technology like stem cell science are widely endorsed by governments keen to reduce spiralling healthcare costs, clinicians focused on patient care and patients demanding revolutionary new treatments. The intersections between governments, healthcare settings and community demand are the environment in which companies are operating to secure a profit in a global marketplace. The key questions posed by this book include: Is there an optimum commercial model? And what can emerging companies learn from their predecessors? Extant research on the global stem cell bioeconomy has highlighted the ways that culture, ethics and national politics have influenced and shaped the commercial possibilities for companies entering into the stem cell market and what possibilities exist for negotiating these barriers. Key issues for commercialization in particular include raising money to conduct research, dealing with regulatory frameworks, developing an intellectual property portfolio, testing technologies in animals and patients, and securing market share. This book explores these issues in examining the future commercial development of the stem cell sciences. Each chapter includes in-depth discussion of case-studies of products undergoing development and the pathways to market that are being adopted. Explicitly focused on the question of commercial optimization, this project is the first of its kind to move beyond concerns about ethics and regulation to examine how products are actually being developed for market. The analysis is considered within a global context, with case-studies being drawn from a diverse range of countries that are commercialising stem cell products. This book features a strong comparative element in order to facilitate a focus on best practice within varied national contexts. Unlike other projects in the field that are focused on human applications only, this book includes discussion of non-human applications of stem cell therapies because this is one of the fastest growing commercial markets to date, and translation of successful products from animal uses to human uses is currently an revolutionary growth area.
List Price: $ 165.00
Price: $ 165.00
Tags: Biohealthcare, Bioscience, Biotech, Cell, Commercializing, Pharma, Publishing, Science, Sciences, Series, Stem, Technology | Posted under Stem Cell Books | Comments Off