Archive for June, 2011
Last Updated on Thursday, 30 June 2011 09:28 Written by Administrator Thursday, 30 June 2011 09:28
Dr Lawrence Stowe from the Stowe Foundation and Dr Frank J Morales Jr offer patients stem cell treatment. This is part two.
Video Rating: 5 / 5
Tags: 21st, Cell, Century, Cures, Part, Snake, Stem | Posted under Stem Cell Videos | 2 Comments
Last Updated on Thursday, 30 June 2011 09:25 Written by Administrator Thursday, 30 June 2011 09:25
Cancer Stem Cells in Solid Tumors (Stem Cell Biology and Regenerative Medicine)
The “cancer stem cell” hypothesis postulates that cancer arises from a subpopulation of tumor-initiating cells or cancer stem cells (CSCs). While the idea of cancer stem cells has been around for more than a hundred years, evidence from the fields of hematology and cancer biology has now demonstrated the critical role of stem cells in hematological malignancies and suggested that these same mechanisms are also central to the initiation, progression, and treatment of solid cancers. Clinical and experimental studies have shown that CSCs exhibit many classical properties of normal stem cells, including a high self-renewal capacity and the ability to generate heterogeneous lineages; the requirement for a specific “niche”/microenvironment to grow; and an increased capacity for self-protection against harsh environments, toxins, and drugs.
Cancer Stem Cells in Solid Tumors represents a detailed overview of cancer stem cells and their role in solid cancers. Comprised of 24 chapters, this volume will provide readers with a comprehensive understanding of this important and evolving field.
Topics covered include:
- Introduction of the CSC hypothesis
- Historical perspectives and the contributing lessons from leukemia
- Current knowledge regarding the identification and role of CSCs in various forms of solid cancer including breast, brain, colorectal, pancreatic, prostate, melanoma, lung, ovarian, hepatocellular, and head and neck cancer
- Molecular pathways involved in driving CSC function, with a particular focus on the novel convergence of embryonic and tumorigenic signaling pathways
- In vitro and in vivo assays, model systems, and imaging modalities for studying CSCs
- The clinical importance of CSCs for cancer management and treatment, including important implications for prognosis, prediction, and treatment resistance
- Consideration of the controversy surrounding the CSC hypothesis and important unanswered questions in this field
This collective work was written by a group of prominent international experts in cancer biology, oncology, and/or stem cell biology. It will serve as a valuable resource for established researchers, professors, health care professionals, and students in the medical and scientific community who are investigating stem cells and/or oncology.
List Price: $ 209.00
Price: $ 177.79
Tags: Biology, Cancer, Cell, cells, Medicine, Regenerative, Solid, Stem, Tumors | Posted under Stem Cell Books | Comments Off
Last Updated on Wednesday, 29 June 2011 09:28 Written by Administrator Wednesday, 29 June 2011 09:28
This lecture, by Dr. Nadia Rosenthal, discusses the role of stem cells in the regeneration and repair of tissues, and their possible medicinal application through the harnessing of their regenerative properties. HHMI description: Human tissues vary in their ability to heal and regenerate. The nervous system has weak powers of regeneration, while the skin is quick to make new cells for repair. Mammalian muscle cells are intermediate in their ability to regenerate. Human muscle can regenerate in response to minor wounds and normal wear and tear, but humans will not grow a new bicep, for example, in response to amputation. The heart is the most important muscle in the body and yet has feeble regenerative capabilities. Research into the wholesale production of new replacement organs and limbs is in its infancy, but research into enhancing normal levels of regeneration is progressing rapidly. Recent discoveries concerning the location and characteristics of adult stem cells and the signals that wounded tissue produces to activate stem cells have increased our understanding of regeneration. Insulin-like growth factor 1 (IGF1) is an example of an important stem cell communication molecule. If the activity of the growth factor is experimentally enhanced, muscle regeneration improves.
Video Rating: 4 / 5
Tags: Aging, cells, Part, Stem | Posted under Stem Cell Videos | 7 Comments
Last Updated on Wednesday, 29 June 2011 09:28 Written by Administrator Wednesday, 29 June 2011 09:28
Mesenchymal Stem Cells: Methods and Protocols (Methods in Molecular Biology)
For over forty years, mesenchymal stem cells (MSCs) have been scrutinized and studied, garnering much attention due to their broad therapeutic efficacy. In this essential book, leaders in the field were assembled to contribute detailed methodologies for the isolation and characterization of human and rodent MSCs. Cutting edge and easy to use, this book is the perfect resource for scientists attempting to pursue this important and ever-developing field of research.
List Price: $ 109.00
Price: $ 91.73
Tags: Biology, cells, Mesenchymal, Methods, Molecular, Protocols, Stem | Posted under Stem Cell Books | Comments Off